講者：林郁真教授
演講題目：The Occurrence and
Phototransformation of Pharmaceuticals in Aqueous Environments in Taiwan
演講時間：3/14（五）15:30~17:20
演講地點：普通館 101
主持人：吳嘉文教授
Dr.
Angela Yu-Chen Lin
Email: yuchenlin@ntu.edu.tw
Website:
http://homepage.ntu.edu.tw/~yuchenlin/
Dr.
Angela Yu-Chen Lin is an Associate Professor in the Graduate Institute of
Environmental Engineering at National Taiwan University. She received her B.S.
degree from Caltech in 1999, and M.S. and Ph.D. degrees in Environmental
Engineering from Stanford University in 2005. She worked at Kennedy/Jenks
Consultants for a year before joining National Taiwan University faculty in
2006. Dr. Lin’s research and teaching interests are in the area of
environmental photochemistry, analytical chemistry, fate (natural attenuation) and
transport of contaminants in aqueous environments, water recycling and
water/wastewater treatment technology. Dr. Lin has more than thirteen years of
research experience on the occurrence and fate of emerging contaminants such as
pharmaceuticals and personal care products, endocrine disruptors and perfluorinated
chemicals. She has published more than sixty highly cited peer-reviewed professional
papers on the above topics. She was awarded the Young Scholar Academic Research
Award in 2013 (Dr. Ta-You Wu Memorial Award), the most prestigious research
award from National Science Council in Taiwan.
藥物於台灣環境水體之流佈與自然光降解宿命
The Occurrence and
Phototransformation of Pharmaceuticals in
Aqueous Environments
in Taiwan
林郁真(Angela Yu-Chen Lin)
台灣大學環境工程學研究所(yuchenlin@ntu.edu.tw)
Abstract
Water scarcity has long been an issue,
forcing us to rely increasingly on degraded water sources such as recycled
wastewaters for drinking water. Water resources are prone to pollution through
natural and anthropogenic contaminations, resulting in death and disease
worldwide. A major source of water pollution is the treated, undertreated and
untreated wastewaters released from wastewater treatment plants (WWTPs). In
Taiwan, hospitals and sewage treatment plants also release their effluents into
neighboring waterways. Therefore, all pollutants not completely removed during
the treatment process are released and enter the receiving water bodies. Among
these are pharmaceuticals that have raised significant concerns in the
twenty-first century.
Pharmaceuticals
undergo various natural attenuation process in environmental waters, including
biotic (biodegradation, bioaccumulation) and abiotic (hydrolysis, photolysis,
sorption, oxidation) degradation. Among these elimination processes,
sunlight-mediated photodegradation may occur via direct and indirect pathways
and have reported to significantly reduce the predicted environmental concentrations
of various pharmaceuticals. Direct photolysis occurs through light absorption
by the chemical itself and leads to chemical bond cleavage. Indirect photolysis
involves light absorption by dissolved organic matter (DOM), nitrates, nitrites
and bicarbonate in the aqueous environments, producing reactive species that
react with target pharmaceuticals.
Over hundreds of commonly used
pharmaceuticals (antibiotics, estrogens, NSAIDs, lipid-regulators, controlled
substances, etc) were investigated and many were identified in the effluents of
hospitals/WWTPs/drug production facilities/animal husbandries, rivers,
reservoirs and even groundwater systems in Taiwan. Once pharmaceuticals are
released into waterways, it is important to fully understand their
phototransformation potential, their fate, in the natural water bodies to
predict the overall risk for exposure to these compounds.
Keywords: Pharmaceuticals, Photodegradation, Natural Attenuation,
Occurrence
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